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Publications
Field of Biospectroscopy
Nummer/ number | Titel | Autoren / authors | Zeitschrift / magazin | Jahr/ year | DOI | PDF nur auf Anfrage | Link | |
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269 | Subjective cognitive complaints and blood biomarkers of neurodegenerative diseases: a longitudinal cohort study | Perna, L., Stocker, H., Burow, L., Beyer, L., Trares, K., Kurz, C., Gürsel, S., Holleczek, B., Tatò, M., Beyreuther, K., Mons, U., Gerwert, K., Perneczky, R., Schöttker, B., Brenner, H. | Alzheimer’s Research & Therapy | 2023 | 198 (15) | 10.1186/s13195-023-01341-3 | ||
268 | Serum neurofilament light chain does not detect self-reported treatment-related fluctuations in chronic inflammatory demyelinating polyneuropathy | Poser, P.L., Sajid, G.S., Beyer, L., Hieke1, A., Schumacher, A., Horstkemper, L., Karl, A.-S., Grüter, T., Sgodzai1, M., Pitarokoili, K., Gerwert, K., Gold, R., Fisse, A.L., Gisevius, B., Motte, J. | european journal of neurology | 2023 | 10.1111/ene.16023 | |||
267 | High cholesterol levels change the association of biomarkers of neurodegenerative diseases with dementia risk: Findings from a population-based cohort | Perna, L., Mons, U., Stocker, H., Beyer, L., Beyreuther, K., Trares, K., Holleczek, B., Schöttker, B., Perneczky, R., Gerwert, K., Brenner, H. | Alzheimer & Dementia | 2023 | 19 (7) 2913-2922 | 10.1002/alz.12933 | ||
266 | Fast and label-free automated detection of microsatellite status in early colon cancer using artificial intelligence integrated infrared imaging | Gerwert, K., Schörner, S. , Großerueschkamp, F., Kraeft, A.-L., Schuhmacher, D., Sternemann, C., Feder, I. S., Wisser, S., Lugnier, C., Arnold, D., Teschendorf, C., Mueller, L., Timmesfeld, N., Mosig, A., Reinacher-Schick, A., Tannapfel, A. | European Journal of Cancer | 2023 | 182, 122-131 | 10.1016/j.ejca.2022.12.026 | ||
265 | Association of Kidney Function With Development of Alzheimer Disease and Other Dementias and Dementia-Related Blood Biomarkers | Stocker, H., Beyer, L., Trares, K., Perna, L., Rujescu, D., Holleczek, B., Beyreuther, K., Gerwert, K., Schöttker, B., Brenner, H. | JAMA Network Open | 2023 | 6 (1) | 10.1001/jamanetworkopen.2022.52387 | ||
264 | Amyloid-beta misfolding and GFAP predict risk of clinical Alzheimer’s disease diagnosis within 17 years | Beyer, L., Stocker, H., Rujescu, D., Holleczek, B., Stockmann, J., Nabers, A., Brenner, H., Gerwert, K. | Alzheimer & Dementia | online: 2022 / print: 2023 | (19) 1020-1028 | 10.1002/alz.12745 | ||
263 | Association of plasmabiomarkers, p-tau181, glial fibrillary acidic protein, and neurofilament light, with intermediate and long-term clinical Alzheimer's disease risk: Results from a prospective cohort followed over 17 years | Stocker, H., Beyer, L., Perna, L., Rujescu, D., Holleczek, B., Beyreuther, K., Stockmann, J., Schöttker1, B., Gerwert, K., Brenner, H. | Alzheimer & Dementia | 2022 | 19 (1) 25-35 | 10.1002/alz.12614 | ||
262 | A Framework for Falsifiable Explanations of Machine Learning Models with an Application in Computational Pathology | Schuhmacher, D., Schoerner, S., Kuepper, C., Grosserueschkamp, F., Sternemann, C., Lugnier, C., Kraeft, A.-L., Juette, H., Tannapfel, A., Reinacher-Schick, A., Gerwert, K., Mosig, A. | medRxiv | 2021 | 10.1101/2021.11.01.21265738 | |||
261 | Diagnostics and Therapy Assessment Using Label-Free Raman Imaging | El-Mashtoly, S.F., Gerwert, K. | Analytical Chemistry | 2021 | 10.1021/acs.analchem.1c04483 | |||
260 | Aß misfolding in blood plasma is inversely associated with body mass index even in middle adulthood | Möllers, T., Stocker, H., Perna, L., Nabers, A., Rujescu, D., Hartmann, A.M., Holleczek, B., Schöttker, B., Gerwert, K., Brenner, H. | Alzheimer's research & therapy | 2021 | 13 (1) 1-9 | 10.1186/s13195-021-00889-2 | ||
259 | Correction to: Amyloid-ß misfolding as a plasma biomarker indicates risk for future clinical Alzheimer’s disease in individuals with subjective cognitive decline | Stockmann, J., Verberk, I.M.W., Timmesfeld, N., Denz, R., Budde, B., Lange-Leifhelm, J., Scheltens, P., van der Flier, W.M., Nabers, A., Teunissen, C.E., Gerwert, K. | Alzheimer's Research & Therapy | 2021 | 13 (1), 1-3 | 10.1186/s13195-021-00770-2 | ||
258 | Shape decomposition algorithms for laser capture microdissection | Selbach, L., Kowalski, T,, Gerwert, K., Buchin, M., Mosig, A. | Algorithms for Molecular Biology | 2021 | 16, 1-17 | 10.1186/s13015-021-00193-6 | ||
257 | End-to-end Multiple Instance Learning for Whole-Slide Cytopathology of Urothelial Carcinoma | Butke, J., Frick, T., Roghmann, F., El-Mashtoli, S.F., Gerwert, K., Mosig, A. | MICCAI Workshop on Computational Pathology | 2021 | 57-68 | |||
256 | Automated detection of microsatellite status in early colon cancer (CC) using artificial intelligence (AI) integrated infrared (IR) imaging on unstained samples from the AIO ColoPredictPlus 2.0 (CPP) registry study | Großerueschkamp, F., Schörner, S.M., Kraeft, A.-L., Schuhmacher, D., Sternemann, C., Jütte, H., Feder, I., Wisser, S., Lugnier, C., Overheu, O., Arnold, D., Teschendorf, C., Mueller, L., Uhl, W., Timmesfeld, N., Mosig, A., Reinacher-Schick, A., Gerwert, K., Tannapfel, A. | Annals of Oncology | 2021 | 32, S531-S532 | 10.1016/j.annonc.2021.08.907 | ||
255 | Advances in digital pathology: from artificial intelligence to label-free imaging | Großerueschkamp, F., Jütte, H., Gerwert, K., Tannapfel, A. | Visceral Medicine | 2021 | 37, 482-490 | 10.1159/000518494 | ||
254 | The association between plasma biomarkers, p-tau181, glial fibrillary acidic protein, and neurofilament light and clinical AD risk: results from prospective cohort study followed over 17 years | Stocker, H., Beyer, L., Perna, L., Schöttker, B., Gerwert, K., Brenner, H. | Alzheimer's Association International Conference | 2021 | ||||
253 | The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson's disease brain as revealed by multicolor STED microscopy | Moors, T.E., Maat, C.A., Niedieker, D., Mona, D., Petersen, D., Timmermans-Huisman, E., Kole, J., El-Mashtoly, S.F., Spycher, L., Zago, W., Barbour, R., Mundigl, O., Kaluza, K., Huber, S., Hug, M.N., Kremer, T., Ritter, M., Dziadek, S., Geurts, J.J.G., Gerwert, K., Britschgi, M., van de Berg, W.D.J. | Acta Neuropathologica | 2021 | 10.1007/s00401-021-02329-9 | |||
252 | Quantum Cascade Laser-Based Infrared Imaging as a Label-Free and Automated Approach to Determine Mutations in Lung Adenocarcinoma | Goertzen, N., Pappesch, R., Fassunke, J., Brüning, T., Ko, Y.-D., Schmidt, J., Großerueschkamp, F., Buettner, R., Gerwert, K. | The American Journal of Pathology | 2021 | Volume 191, Issue 7, 1269-1280 | 10.1016/j.ajpath.2021.04.013 | ||
251 | Time-resolved spectroscopic andelectrophysiological data reveal insights in thegating mechanism of anion channelrhodopsin | Dreier, M.-A., Althoff, P., Norahan, M.J., Tennigkeit, S.A., El-Mashtoly, S.F., Lübben, M., Kötting, C., Rudack, T., Gerwert, K. | Communications Biology | 2021 | 4, 578 | 10.1038/s42003-021-02101-5 | ||
250 | Genetic predisposition, Aß misfolding in blood plasma, and Alzheimer’s disease | Stocker, H., Nabers, A., Perna, L., Möllers, T., Rujescu, D., Hartmann, A.M., Holleczek, B., Schöttker, B., Stockmann, J., Gerwert, K., Brenner, H. | Translational psychiatry | 2021 | 11 (1), 1-11, 6779-6783 | 10.1038/s41398-021-01380-0/ | ||
249 | Microsecond-Resolved Infrared Spectroscopy on Nonrepetitive Protein Reactions by Applying Caged Compounds and Quantum Cascade Laser Frequency Combs | Norahan, M.J., Horvath, R., Woitzik, N., Jouy, P., Eigenmann, F., Gerwert, K., Kötting, C. | Analytical Chemistry | 2021 | 10.1021/acs.analchem.1c00666/ | |||
248 | A representation learning approach for recovering scatter?corrected spectra from Fourier?transform infrared spectra of tissue samples | Raulf, A.P., Butke, J., Menzen, L., Küpper, C., Großerueschkamp, F., Gerwert, K., Mosig, A. | Journal of Biophotonics | 2021 | (14) 3 | 10.1002/jbio.202000385 | ||
247 | A Framework for Falsifiable Explanations of Machine Learning Models with an Application in Computational Pathology | Schuhmacher, D., Schörner, S., Küpper, C., Großerueschkamp, F., Sternemann, C., Lugnier, C., Kraeft, A.-L., Jütte, H., Tannapfel, A., Reinacher-Schick, A., Gerwert, K., Mosig, A. | redRxiv | 2021 | ||||
246 | Application of Label-Free Proteomics for Quantitative Analysis of Urothelial Carcinoma and Cystitis Tissue | Witzke, K. E., Großerueschkamp, F., Gerwert, K., Sitek, B. | Methods in Molecular Biology (Clifton, NJ) 2228, 283-292 | 2021 | ||||
245 | The Ras Dimer Structure | Rudack, T., Teuber, C., Scherlo, M., Güldenhaupt, J., Schartner, J., Lübben, M., Klare, J.P., Gerwert, K., Kötting, C. | Chemical Science | 2021 | 12, 8178 - 8189 | 10.1039/D1SC00957E | ||
244 | Aß misfolding in blood plasma measured by immuno-infrared-sensor as an age-independent risk marker of Alzheimer's disease | Möllers, T., Stocker, H., Perna, L., Nabers, A., Rujescu, D., Hartmann, A.M., Holleczek, B., Schöttker, B., Gerwert, K., Brenner, H. | Alzheimer's Dement. | 2021 | 13:e12151 | 10.1002/dad2.12151 | ||
243 | TDP-43 as structure-based biomarker in amyotrophic lateral sclerosis | Beyer, L., Günther, R., Koch, J.C., Klebe, S., Hagenacker, T., Lingor, P., Biesalski, A.-S., Hermann, A., Nabers, A., Gold, R., Lönges, L., Gerwert, K. | Annals of Clinical and Translational Neurology | 2021 | 8 (1), 271-277 | 10.1002/acn3.51256 | ||
242 | Amyloid-ß misfolding as a plasma biomarker indicates risk for future clinical Alzheimer’s disease in individuals with subjective cognitive decline | Stockmann, J., Verberk, I.M.W., Timmesfeld, N., Denz, R., Budde, B., Lange-Leifhelm, J., Scheltens, P., van der Flier, W., Nabers, A., Teunissen, C.E., Gerwert, K. | Alzheimer's Research & Therapy | 2020 | 10.1186/s13195-020-00738-8 | |||
241 | Label-free vibrational imaging of different Aß plaque types in Alzheimer’s disease reveals sequential events in plaque development | Röhr, D., Boon, B.D.C., Schuler, M., Kremer, K., Hoozemans, J.J.M., Bouwman, F.H., El-Mashtoly, S.F., Nabers, A., Groserueschkamp, F., Rozemuller, A.M.J., Gerwert, K. | Acta Neuropathol Commun | 2020 | 10.1186/s40478-020-01091-5 | |||
240 | TDP-43 as structure-based biomarker in amyotrophic lateral sclerosis | Beyer, L., Günther, R., Koch, J.C., Klebe, S., Hagenacker, T., Lingor, P., Biesalski, A.-S., Hermann, A., Nabers, A., Gold, R., Tönges, L., Gerwert, K. | Annals of Clinical and Translational Neurology | 2020 | 10.1002/acn3.51256 | |||
239 | Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study | Guo, S., Beleites, C., Neugebauer, U., Abalde-Cela, S., Afseth, N.K., Alsamad, F., Anand, S., Araujo-Andrade, C., Askrabic, S., Avci, E., Baia, M., Baranska, M., Baria, E., de Carvalho, L.A.E.B., de Bettignies, P., Bonifacio, A., Bonnier, F., Brauchle, E.M., Byrne, H.J., Chourpa, I., Cicchi, R., Cuisinier, F., Culha, M., Dahms, M., David, C., Duponchel, L., Duraipandian, S., El-Mashtoly, S.F., Ellis, D.I., Eppe, G., Falgayrac, G., Gamulin, O., Gardner, B., Gardner, P., Gerwert, K., Giamarellos-Bourboulis, E.J., Gizurarson, S., Gnyba, M., Goodacre, R., Grysan, P., Guntinas-Lichius, O., Helgadottir, H., Grosev, V.M., Kendall, C., Kiselev, R., Kölbach, M., Krafft, C., Krishnamoorthy, S., Kubryck, P., Lendl, B., Loza-Alvarez, P., Lyng, F.M., Machill, S., Malherbe, C., Marro, M., Marques, M.P.M., Matuszyk, E., Morasso, C.F., Moreau, M., Muhamadali, H., Mussi, V., Notingher, I., Pacia, M.Z., Pavone, F.S., Penel, G., Petersen, D., Piot, O., Rau, J.V., Richter, M., Rybarczyk, M.K., Salehi, H., Schenke-Layland, K., Schlücker, S., Schosserer, M., Schütze, K., Sergo, V., Sinjab, F., Smulko, J., Sockalingum, G.D., Stiebing, C., Stone, N., Untereiner, V., Vanna, R., Wieland, K., Popp, J., Bocklitz, T. | Anal. Chem. | 2020 | 10.1021/acs.analchem.0c02696 | |||
238 | Shape Decomposition Algorithms for LaserCapture Microdissection | Selbach, L., Kowalski, T., Gerwert, K., Buchin, M., Mosig, A. | 20th International Workshop on Algorithms in Bioinformatics (WABI 2020) | 2020 | 10.4230/LIPIcs.WABI.2020.13 | |||
237 | The Effect of (-)-Epigallocatechin-3-Gallate on the Amyloid-β Secondary Structure | Acharya, A., Stockmann, J., Beyer, L., Rudack, T., Nabers, A., Gumbart, J.C., Gerwert, K., Batista, V.S. | Biophys J. | 2020 | 10.1016/j.bpj.2020.05.033 | + | ||
236 | Label-free, automated classification of microsatellite status in colorectal cancer by infrared imaging | Kallenbach-Thieltges, A., Großerüschkamp, F., Jütte, H., Kuepper, C., Reinacher-Schick, A., Tannapfel, A., Gerwert, K. | Scientific Reports | 2020 | 10: 10161 | 10.1038/s41598-020-67052-z | ||
235 | Struktur-Biomarker zur Früherkennung von Morbus Alzheimer | Stockmann, J., Gerwert, K. | Biospektrum | 2020 | 03/2020 (26) 259-261 (2020), DOI: 10.1007/s12268-020-1381-7 | 10.1007/s12268-020-1381-7 | ||
234 | Grayscale representation of infrared microscopy images by extended multiplicative signal correction for registration with histological images | Trukhan, S., Tafintseva, V., Tøndel, K., Großerüschkamp, F, Mosig, A., Kovalev, V., Gerwert, K., Kohler, A. | J. Biophotonics. | 2020 | 13:e201960223 | 10.1038/s41598-020-67052-z | ||
233 | Toward noninvasive follow-up of low-risk bladder cancer--Rationale and concept of the UroFollow trial | Benderska-Söder, N., Hovanec, J., Pesch, B., Goebell, P. J., Roghmann, F., Noldus, J., Rabinovich, J., Wichert, K., Gleichenhagen, J., Käfferlein, H. U., Köhler, C. U., Johnen, G., Kernig, K., Hakenberg, O., Jahn, D., Todenhöfer, T., Stenzl, A., Gleissner, J., Gerwert, K., El-Mashtoly, S., Behrens, T., Brüning, T., Schmitz-Dräger, B. J. | Urologic Oncology | 2020 | https://doi.org/10.1016/j.urolonc.2020.01.006 | |||
232 | Lamprey Parapinopsin ("UVLamP"): a Bistable UV-Sensitive Optogenetic Switch for Ultrafast Control of GPCR Pathways | Eickelbeck, D., Rudack, T., Tennigkeit, S.A., Surdin, T., Karapinar, R., Schwitalla, J.-C., Mücher, B., Shulman, M., Scherlo, M., Althoff, P., Mark, M.D., Gerwert, K., Herlitze, S. | ChemBioChem | 2020 | 21: 612-617 | https://doi.org/10.1002/cbic.201900485 | ||
231 | Estimation of Protein-Ligand Unbinding Kinetics Using Non-Equilibrium Targeted Molecular Dynamics Simulations | Wolf, S., Amaral, M., Lowinski, M., Vallée, F., Musil, D., Güldenhaupt, J., Dreyer, M.K., Bomke, J., Frech, M., Schlitter, J., Gerwert, K. | Journal of Chemical Information and Modeling | 2019 | 59: 5135-5147 | https://doi.org/10.1021/acs.jcim.9b00592 | ||
230 | Label-Free Molecular Fingerprint-Based Cytopathology | El-Mashtoly, S.F., Gerwert, K. | GIT Imaging & Microscopy | 2019 | 21: 3/2019, 23–25 | |||
229 | Prediction of Alzheimer's disease diagnosis within 14 years through Aß misfolding in blood plasma compared to APOE4 status, and other risk factors. | Stocker, H., Nabers, A., Perna, L., Möllers, T., Rujescu, D., Hartmann, A., Holleczek, B., Schöttker, B., Gerwert, K., Brenner, H. | Alzheimer's & Dementia | 2019 | 16: 283-291 | https://doi.org/10.1016/j.jalz.2019.08.189 | ||
228 | High-content screening Raman spectroscopy (HCS-RS) of panitumumab-exposed colorectal cancer cells | Mondol, A.S., El-Mashtoly, S.F., Frick, T., Gerwert, K., Poppa, J., Schie, I.W. | Analyst | 2019 | 144: 6098-6107 | https://doi.org/10.1039/C9AN01176E | ||
227 | Fast Non-invasive Diagnosis of Cervical Cancer by Coherent anti-Stokes Raman Scattering | Aljakouch, K., Hilal, Z., Daho, I., Schuler, M., Krauß, S.D., Yosef, H.K., Dierks, J., Mosig, A., Gerwert, K., El-Mashtoly, S.F. | Analytical Chemistry | 2019 | 91: 13900−13906 | https://doi.org/10.1021/acs.analchem.9b03395 | ||
226 | Reversible Immuno-Infrared Sensor for the Detection of Alzheimer's Disease Related Biomarkers | Budde, B., Schartner, J., Tönges, L., Kötting, C., Nabers, A., Gerwert, K. | ACS Sensors | 2019 | 4: 1851-1856 | https://doi.org/10.1021/acssensors.9b00631 | ||
225 | GTP Hydrolysis Without an Active Site Base: A Unifying Mechanism for Ras and Related GTPases | Calixto, A.R., Moreira, C., Pabis, A., Kötting, C., Gerwert, K., Rudack, T., Kamerlin, S.C.L. | Journal of the American Chemical Society (JACS) | 2019 | 141: 10684-10701 | https://doi.org/10.1021/jacs.9b03193 | ||
224 | Comparison of the molecular properties of retinitis pigmentosa P23H and N15S amino acid replacements in rhodopsin | Mitchell, J., Balem, F., Tirupula, K., Man, D., Dhiman, H.K., Yanamala, N., Ollesch, J., Planas-Iglesias, J., Jennings, B.J., Gerwert, K., Iannaccone, A., Klein-Seetharaman, J. | PLoS ONE | 2019 | 14(5): e0214639 | https://doi.org/10.1371/journal.pone.0214639 | ||
223 | Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes. | Shahmoradian, S.H., Lewis, A.J., Genoud, C., Hench, J., Moors, T.E., Navarro, P.P., Castaño-Díez, D., Schweighauser, G., Graff-Meyer, A., Goldie, K.N., Sütterlin, R.,Huisman, E., Ingrassia, A., de Gier, Y., Rozemuller, A.J.M., Wang, J., De Paepe, A., Erny J., Staempfli, A., Hoernschemeyer, J., Großerüschkamp, F., Niedieker, D., El-Mashtoly, S.F., Quadri, M., Van IJcken, W.F.J., Bonifati, V., Gerwert, K., Bohrmann, B., Frank, S., Britschgi, M., Stahlberg, H., Van de Berg, W.D.J., Lauer, M.E. | Nature Neuroscience | 2019 | 22: 1099–1109 | https://doi.org/10.1038/s41593-019-0423-2 | ||
222 | Deep representation learning for domain adaptable classification of infrared spectral imaging data. | Raulf, A.P., Butke J., Küpper, C., Großerüschkamp, F., Gerwert, K., Mosig, A. | Bioinformatics | 2019 | 36: 287-294 | https://doi.org/10.1093/bioinformatics/btz505 | ||
221 | Unifying photocycle model for light adaptation and temporal evolution of cation conductance in channelrhodopsin-2. | Kuhne, J., Vierock, J., Tennigkeit, S.A., Dreier, M.-A., Wietek, J., Petersen, D., Gavriljuk, K., El-Mashtoly, S.F., Hegemann, P., Gerwert, K. | Proceedings of the National Academy of Sciences (PNAS) | 2019 | 116: 9380-9389 | https://doi.org/10.1073/pnas.1818707116 | ||
220 | An open-source code for Mie extinction extended multiplicative signal correction for infrared microscopy spectra of cells and tissues. | Solheim, J.H., Gunko, E., Petersen, D., Großerüschkamp, F., Gerwert, K., Kohler, A. | Journal of Biophotonics | 2019 | 12: e201800415 | https://doi.org/10.1002/jbio.201800415 | ||
219 | Aß and tau structure-based biomarkers for a blood- and CSF-based two-step recruitment strategy to identify patients with dementia due to Alzheimer's disease | Nabers, A., Hafermann, H., Wiltfang, J., Gerwert, K. | Alzheimer's & Dementia: Diagn., Assess. & Dis. Monit. | 2019 | 11: 257-263 | https://doi.org/10.1016/j.dadm.2019.01.008 | ||
218 | Design of an ultra-fast G protein switch based on a mouse melanopsin variant | Tennigkeit, S.A., Karapinar, R., Rudack, T., Dreier, M.-A., Althoff, P., Eickelbeck, D., Surdin, T., Grömmke, M., Mark, M.D., Spoida, K., Lübben, M., Höweler, U., Herlitze, S., Gerwert, K. | ChemBioChem | 2019 | 20: 1766-1771 | https://doi.org/10.1002/cbic.201900110 | ||
217 | Integrated Fourier Transform Infrared Imagingand Proteomics for Identification of a CandidateHistochemical Biomarker in Bladder Cancer | Witzke, K., Großerueschkamp, F., Jütte, H.,Horn, M., Roghmann, F., von Landenberg, N., Bracht, T., Kallenbach-Thieltges, A., Käfferlein, H., Brüning, T., Schork, K., Eisenacher, M., Marcus, K., Noldus, J., Tannapfel, A., Sitek, B., Gerwert, K. | The American Journal of Pathology | 2019 | 189: 619-631 | https://doi.org/10.1016/j.ajpath.2018.11.018 | ||
216 | Tracking Pore Hydration in Channelrhodopsin by Site-Directed Infrared Active-Azido Probes | Krause, B.S., Kaufmann,J.C.D., Kuhne, J., Vierock, J., Huber, T., Sakmar, T.P., Gerwert, K., Bartl, F., Hegemann, P. | Biochemistry | 2019 | 58:1275-1286 | https://pubs.acs.org/doi/10.1021/acs.biochem.8b01211 | ||
215 | FTIR Spectroscopy: A Comprehensive Biological Investigator | Mann, D., Köttig, C., Gerwert, K. | BioPhotonics | 2018 | November/December 2018, 30-35 | |||
214 | Label-free Digital Pathology | Großerüschkamp, F., Gerwert, K. | GIT Laboratory Journal | 2018 | 5/2018:33-35 | |||
213 | Exploring the efficacy and cellular uptake of sorafenib in colon cancer cells by Raman micro-spectroscopy | Yosef, H.K., Frick, T., Hammoud, M.K., Maghnouj, A., Hahn, S., Gerwert, K., El-Mashtoly, S.F. | Analyst | 2018 | 143: 6069-6078 | https://doi.org/10.1039/C8AN02029A | ||
212 | Raman micro-spectroscopy monitors acquired resistance to targeted cancer therapy at the cellular level | Hammoud, M.K., Yosef, H.K., Lechtonen, T., Aljakouch, K., Schuler, M., Alsaidi, W., Daho, I., Maghnouj, A., Hahn, S., El-Mashtoly, S.F., Gerwert, K. | Scientific Reports | 2018 | 8: 15278 | https://doi.org/10.1038/s41598-018-33682-7 | ||
211 | Monitoring transient events in infrared spectra using localmode analysis | Massarczyk, M., Schlitter, J., Kötting, C., Rudack, T., Gerwert, K. | Proteins | 2018 | 86, 1013–1019, DOI: 10.1002/prot.25536 | https://pubmed.ncbi.nlm.nih.gov/30019772/ | ||
210g | Zeitaufgelöst und markerfrei gemessene ligandeninduzierte Konformationsänderungen von HSP90 – hin zu einem Konformationsaktivitätsscreening für die Wirkstoffentwicklung | Güldenhaupt, J., Amaral, M., Kötting, C., Schartner, J., Musil, D., Frech, M., Gerwert, K. | Angewandte Chemie | 2018 | 57: 10103-10108 | https://doi.org/10.1002/ange.201802603 | ||
210e | Ligand-induced conformational changes in HSP90 monitored time resolved and label free – towards a conformational activity screening for drug discovery | Güldenhaupt, J., Amaral, M., Kötting, C., Schartner, J., Musil, D., Frech, M., Gerwert, K. | Angewandte Chemie International Edition | 2018 | 57: 9955-9960 | https://doi.org/10.1002/anie.201802603 | ||
209 | Hierarchical deep convolutional neural networks combine spectral and spatial information for highly accurate Raman-microscopy-based cytopathology | Krauß, S.D., Roy, R., Yosef, H.K., Lechtonen, T., El-Mashtoly, S.F., Gerwert, K., Mosig, A. | Journal of Biophotonics | 2018 | 11: e201800022 | https://doi.org/10.1002/jbio.201800022 | ||
208 | Quantum Cascade Laser-Based Infrared Microscopy for Label-Free and Automated Cancer Classification in Tissue Sections | Kuepper, C., Kallenbach-Thieltges, A., Juette, H., Tannapfel, A., Großerueschkamp, F., Gerwert, K. | Scientific Reports | 2018 | 8: 7717 | https://doi.org/10.1038/s41598-018-26098-w | ||
207 | Highly stable Protein Immobilization via Maleimido-Thiol Chemistry to Monitor Enzymatic Activity | Schartner, J., Güldenhaupt, J., Gaßmeyer, S.K., Rosga, K., Kourist, R., Gerwert, K., Kötting, C. | Analyst | 2018 | 143: 2276-2284 | https://doi.org/10.1039/c8an00301g | ||
206 | Label-free identification of myopathological features with coherent anti-Stokes Raman scattering | Niedieker, D., Großerüschkamp, F., Schreiner, A., Barkovits, K., Kötting, C., Marcus, K., Gerwert, K., Vorgerd, M. | Muscle Nerve | 2018 | 58: 456-459 | https://doi.org/10.1002/mus.26140 | ||
205g | Raman-mikrospektroskopischer Nachweis für den Metabolismus eines Tyrosinkinase-Inhibitors, Neratinib, in Krebszellen | Aljakouch, K., Lechtonen, T., Yosef, H.K., Hammoud, M.K., Alsaidi, W., Kötting, C., Mügge, C., Kourist, R., El-Mashtoly, S.F., Gerwert, K. | Angewandte Chemie | 2018 | 130: 7370-7374 | https://doi.org/10.1002/ange.201803394 | ||
205e | Raman Microspectroscopic Evidence for the Metabolism of a Tyrosine Kinase Inhibitor, Neratinib, in Cancer Cells | Aljakouch, K., Lechtonen, T., Yosef, H.K., Hammoud, M.K., Alsaidi, W., Kötting, C., Mügge, C., Kourist, R., El-Mashtoly, S.F., Gerwert, K. | Angewandte Chemie International Edition | 2018 | 57: 7250-7254 | https://doi.org/10.1002/ange.201803394 | ||
204 | Amyloid blood biomarker detects Alzheimer's disease | Nabers, A., Perna, L., Lange, J., Mons, U., Schartner, J., Güldenhaupt, J., Saum, K.-U., Janelidze, S., Holleczek, B., Rujescu, D., Hansson, O., Gerwert, K., Brenner, H. | EMBO Molecular Medicine | 2018 | 10: e8763 | https://doi.org/10.15252/emmm.201708763 | ||
203 | Specific Substates of Ras To Interact with GAPs and Effectors: Revealed by Theoretical Simulations and FTIR Experiments | Li, Y., Zhang, Y., Groserüschkamp, F., Stephan, S., Cui, Q., Kötting, C., Xia, F., Gerwert, K. | The Journal of Physical Chemistry Letters | 2018 | 9: 1312-1317 | https://doi.org/10.1021/acs.jpclett.8b00342 | ||
202 | The Protonation States of GTP and GppNHp in Ras Proteins | Mann, D., Güldenhaupt, J., Schartner, J., Gerwert, K., Kötting, C. | Journal of Biological Chemistry (JBC) | 2018 | 293: 3871-3879 | https://doi.org/10.1074/jbc.ra117.001110 | ||
201 | Integrating spatial, morphological, and textural information for improved cell type differentiation using Raman microscopy | Krauß, S.D., Yosef, H.K., Lechtonen, T., Jütte, H., Tannapfel, A., Käfferlein, H.U., Brüning, T., Roghmann, F., Noldus, J., El-Mashtoly, S.F., Gerwert, K., Mosig, A. | Journal of Chemometrics | 2017 | 32: e2973 | https://doi.org/10.1002/cem.2973 | ||
200 | Channelrhodopsin reveals its dark secrets | Gerwert, K. | Science | 2017 | 358: 1000-1001 | https://doi.org/10.1126/science.aar2299 | ||
199 | Dynamical Binding Modes Determine Agonistic and Antagonistic Ligand Effects in the Prostate-Specific G-Protein Coupled Receptor (PSGR) | Wolf, S., Jovancevic, N., Gelis, L., Pietsch, S., Hatt, H., Gerwert, K. | Scientific Reports | 2017 | 7: 16007 | https://doi.org/10.1038/s41598-017-16001-4 | ||
198 | Lewy pathology in Parkinson's disease consists of a crowded organellar membranous medley | Shahmoradian, S.H., Genoud, C., Graff-Meyer, A., Hench, J., Moors, T., Schweighauser, G., Wang, J., Goldie, K.N., Suetterlin, R., Castano-Diez, D., Perez-Navarro, P., Huisman, E., Ipsen, S., Ingrassia, A., de Gier, Y., Rozemuller, A.J.M., Da Paepe, A., Erny, J., Staempfli, A., Hoernschemeyer, J., Grosserueschkamp, F., Niedieker, D., El-Mashtoly, S.F., Quadri, M., van Ijcken, W.F.J., Bonifati, V., Gerwert, K., Bohrmann, B., Frank, B., Britschgi, M., Stahlberg, H., van de Berg, W., Lauer, M.E. | bioRxiv | 2017 | https://doi.org/10.1101/137976 | |||
197 | An ATR-FTIR-Sensor Unraveling the Drug Intervention of Methylene Blue, Congo Red, and Berberine on Human Tau and Aß | Schartner, J., Nabers, A., Budde, B., Lange, J., Hoeck, N., Wiltfang, J., Kötting, C., Gerwert, K. | ACS Medicinal Chemistry Letters | 2017 | 8: 710-714 | https://doi.org/10.1021/acsmedchemlett.7b00079 | ||
196 | Non-invasive Diagnosis of High-grade Urothelial Carcinoma in Urine by Raman Spectral Imaging | Yosef, H.K., Krauß, S.D., Lechtonen, T., Jütte, H., Tannapfel, A., Käfferlein, H.U., Brüning, T., Roghmann, F., Noldus, J., Mosig, A., El-Mashtoly, S.F., Gerwert, K. | Analytical Chemistry | 2017 | 89: 6893-6899 | https://doi.org/10.1021/acs.analchem.7b01403 | ||
195 | Common mechanisms of catalysis in small and heterotrimeric GTPases and their respective GAPs | Gerwert, K., Mann, D., Kötting, C. | Biological Chemistry | 2017 | 398: 523-533 | https://doi.org/10.1515/hsz-2016-0314 | ||
194 | Guest Editorial - Highlight: GTP- and ATP-dependent membrane processes | Gerwert, K. | Biological Chemistry | 2017 | 398: 519-521 | https://doi.org/10.1515/hsz-2017-0132 | ||
193 | Der Computer als Mikroskop | Mann, D., Kötting, C., Gerwert, K. | GIT Labor-Fachzeitschrift | 2017 | 3/2017, 39–41 | |||
192 | Spatial and molecular resolution of diffuse malignant mesothelioma heterogeneity by integrating labelfree FTIR imaging, laser capture microdissection and proteomics | Großerüschkamp, F., Bracht, T., Diehl, H.C., Küpper, C., Ahrens, M., Kallenbach-Thieltges, A., Mosig, A., Eisenacher, M., Marcus, K., Behrens, T., Brüning, T., Theegarten, D., Sitek, B., Gerwert, K. | Scientific Reports | 2017 | 7: 44829 | https://doi.org/10.1038/srep44829 | ||
191 | Clinical application of infrared fibre-optic probes for the discrimination of colorectal cancer tissues and cancer grades | Ollesch, J., Zaczek, M., Heise, H. M., Theisen, O., Großerüschkamp, F., Schmidt, R., Morgenroth, K., Philippou, S., Kemen, M., Gerwert, K. | Vibrational Spectroscopy | 2017 | (91) 99-110 | |||
190 | Raman fiber-optical method for colon cancer detection: Cross-validation and outlier identification approach | Petersen, D., Naveedb, P., Ragheb, A., Niedieker, D., El-Mashtoly, S.F., Brechmann, T., Kötting, C., Schmiegel, W.H.,Freier, E., Pox, C., Gerwert, K. | Spectrochimica Acta Part A: Mol. Biomol. Spectrosc. | 2017 | 181: 270-275 | https://doi.org/10.1016/j.saa.2017.03.054 | ||
189 | Local Mode Analysis: Decoding IR Spectra by Visualizing Molecular Details | Massarczyk, M., Rudack, T., Schlitter, J., Kuhne, J., Kötting, C., Gerwert, K. | The Journal of Physical Chemistry B | 2017 | 121: 3483-3492 | https://doi.org/10.1021/acs.jpcb.6b09343 | ||
188 | Asymmetric rhenium tricarbonyl complexes show superior luminescence properties in live cell imaging | Raszeja, L.J., Siegmund, D., Cordes, A.L., Güldenhaupt, J., Gerwert, K., Hahn, S., Metzler-Nolte, N. | Chemical Communications | 2017 | 53: 905-908 | https://doi.org/10.1039/c6cc07553c | ||
187 | Elucidation of Single Hydrogen Bonds in GTPases via Experimental and Theoretical Infrared Spectroscopy | Mann, D., Höweler, U., Kötting, C., Gerwert, K. | Biophysical Journal | 2017 | 112: 66-77 | https://doi.org/10.1016/j.bpj.2016.11.3195 | ||
186 | Mechanism of the intrinsic arginine finger in heterotrimeric G proteins | Mann, D., Teuber, C., Tennigkeit, S.A., Schröter, G., Gerwert, K., Kötting, C. | Proceedings of the National Academy of Sciences (PNAS) | 2016 | 113: E8041-E8050 | https://doi.org/10.1073/pnas.1612394113 | ||
185 | Virtual Staining of Colon Cancer Tissue by Label-free Raman Micro-spectroscopy | Petersen, D., Mavarani, L., Niedieker, D., Freier, E., Tannapfel, A., Kötting, C., Gerwert, K., El-Mashtoly, S.F. | Analyst | 2016 | 142: 1207-1215 | https://doi.org/10.1039/c6an02072k | ||
184 | Unraveling the phosphocholination mechanism of the Legionella pneumophila enzyme AnkX | Gavriljuk, K., Schartner, J., Seidel, H., Dickhut, C., Zahedi, R.P., Hedberg, C., Kötting, C., Gerwert, K. | Biochemistry | 2016 | 55: 4375-4385 | https://doi.org/10.1021/acs.biochem.6b00524 | ||
183 | [FeFe]-Hydrogenase with Chalcogenide Substitutions at the H-Cluster Maintains Full H2 Evolution Activity. | Noth, J., Esselborn, J., Güldenhaupt, J., Brünje, A., Sawyer, A., Apfel, U.P., Gerwert, K., Hofmann, E., Winkler, M., Happe, T. | Angewandte Chemie International Edition | 2016 | 55: 8396-83400 | https://doi.org/10.1002/ange.201511896 | ||
182 | An infrared spectroscopic blood test for non-small cell lung carcinoma and subtyping into pulmonary squamous cell carcinoma or adenocarcinoma. | Ollesch, J., Theegarten, D., Altmayer M., Darwiche, K., Hager, T., Stamatis, G., Gerwert, K. | Biomedical Spectroscopy and Imaging | 2016 | 5: 129-144 | https://doi.org/10.3233/bsi-160144 | x | |
181 | Thirty years of European Conference on Spectroscopy of Biological Molecules celebrated in Ruhr University Bochum | Haris, P.I., Gerwert, K. | Biomedical Spectroscopy and Imaging | 2016 | 5: 99-100 | https://doi.org/10.3233/bsi-160142 | x | |
180 | Label-free classification of colon cancer grading using infrared spectral histopathology. | Kuepper, C., Großerueschkamp, F., Kallenbach-Thieltges, A., Mosig, A., Tannapfel, A., Gerwert, K. | Faraday Discussions | 2016 | 187: 105-118 | https://doi.org/10.1039/c5fd00157a | ||
179 | Amyloid-ß-Secondary Structure Distribution in Cerebrospinal Fluid and Blood Measured by an Immuno-Infrared-Sensor: A Biomarker Candidate for Alzheimer's Disease. | Nabers, A., Ollesch, J., Schartner, J., Kötting, C., Genius, J., Hafermann, H., Klafki, H., Gerwert, K., Wiltfang, J. | Analytical Chemistry | 2016 | 88: 2755-2762 | https://doi.org/10.1021/acs.analchem.5b04286 | ||
178 | An infrared sensor analysing label-free the secondary structure of the Abeta peptide in presence of complex fluids | Nabers, A., Ollesch, J., Schartner, J., Kötting, C., Genius, J., Haußmann, U., Klafki, H., Wiltfang, J., Gerwert, K. | Journal of Biophotonics | 2016 | 3: 224-234 | https://doi.org/10.1002/jbio.201400145 | ||
177 | Fully automated registration of vibrational microspectroscopic images in histologically stained tissue sections. | Yang, C., Niedieker, D., Großerüschkamp, F., Horn, M., Tannapfel, A., Kallenbach-Thieltges, A., Gerwert, K., Mosig, A. | BMC Bioinformatics | 2015 | 16: 396 | https://doi.org/10.1186/s12859-015-0804-9 | ||
176 | Catalysis of GTP hydrolysis by small GTPases at atomic detail by integration of X-ray crystallography, experimental and theoretical IR spectroscopy | Rudack, T., Jenrich, S., Brucker, S., Vetter, I.R., Gerwert, K., Kötting, C. | Journal of Biological Chemistry (JBC) | 2015 | 290: 24079-24090 | https://doi.org/10.1074/jbc.M115.648071 | ||
175 | In vitro prediction of the efficacy of molecularly targeted cancer therapy by Raman spectral imaging | Hesham, K.Y., Mavarani, L., Maghnouj, A., Hahn, S., El-Mashtoly, S.F., Gerwert, K. | Analytical and Bioanalytical Chemistry | 2015 | 407: 8321-8331 | https://doi.org/10.1007/s00216-015-8875-z | ||
174 | Label-free Raman spectroscopic imaging monitors the integral physiologically relevant drug responses in cancer cells | El-Mashtoly, S.F., Yosef, H.K., Petersen, D., Mavarani, L., Maghnouj, A., Hahn, S.A., Kötting, C., Gerwert, K. | Analytical Chemistry | 2015 | 87: 7297-7304 | https://doi.org/10.1021/acs.analchem.5b01431 | ||
173 | Chemical Functionalization of Germanium with Dextran-Brushes for Immobilization of Proteins Revealed by ATR-FTIR Difference Spectroscopy | Schartner, J., Hoeck, N., Güldenhaupt, J., Mavarani, L., Nabers, A., Gerwert, K., Kötting, C. | Analytical Chemistry | 2015 | 87: 7467-7475 | https://doi.org/10.1021/acs.analchem.5b01823 | ||
172 | Integration of Fourier Transform Infrared Spectroscopy, Fluorescence Spectroscopy, Steady-State Kinetics and Molecular Dynamics Simulations of Gai1 distinguishes between the GTP Hydrolysis and GDP Release Mechanism | Schröter, G., Mann, D., Kötting, C., Gerwert, K. | Journal of Biological Chemistry (JBC) | 2015 | 290: 17085-17095 | https://doi.org/10.1074/jbc.M115.651190 | ||
171 | Colocalization of fluorescence and Raman microscopic images for the identification of subcellular compartments: a validation study | Krauß, S.D., Petersen, D., Niedieker, D., Fricke, I., Freier, E., El-Mashtoly, S.F., Gerwert, K., Mosig, A. | Analyst | 2015 | 140: 2360-2368 | https://doi.org/10.1039/c4an02153c | ||
170 | A method for the comparison of multi-platform spectral histopathology (SHP) data sets. | Ergin, A., Großerüschkamp, F., Theisen, O., Gerwert, K., Remiszewski, S., Thompson, C.M., Diem, M. | Analyst | 2015 | 140: 2465-2472 | https://doi.org/10.1039/C4AN01879F | ||
169 | Review: What vibrations tell us about GTPases | Kotting, C., Gerwert, K. | Biological Chemistry | 2015 | 396: 131-144 | https://doi.org/10.1515/hsz-2014-0219 | ||
168b | Early Formation of the Ion-Conducting Pore in Channelrhodopsin-2 | Kuhne, J., Eisenhauer, K., Ritter, E., Hegemann, P., Gerwert, K., Bartl, F. | Angewandte Chemie International Edition | 2015 | 54: 4953-4957 | https://doi.org/10.1002/anie.201410180 | ||
168a | Die frühe Entstehung der ionenleitenden Pore in Channelrhodopsin-2 | Kuhne, J., Eisenhauer, K., Ritter, E., Hegemann, P., Gerwert, K., Bartl, F. | Angewandte Chemie | 2015 | 127: 5037-5041 | https://doi.org/10.1002/ange.201410180 | ||
167 | Marker-free automated histopathological annotation of lung tumour subtypes by FTIR imaging | Großerüschkamp, F., Kallenbach-Thieltges, A., Behrens, T., Brüning, T., Altmayer, M., Stamatis, G., Theegarten, D., Gerwert, K. | Analyst | 2015 | 140: 2114-2120 | https://doi.org/10.1039/C4AN01978D | ||
166 | Infrared spectral marker bands characterizing a transient water wire inside a hydrophobic membrane protein | Wolf, S., Freier, E., Cui, Q., Gerwert, K. | The Journal of Chemical Physics | 2014 | 141: 22D524 | https://doi.org/10.1063/1.4902237 | ||
165 | Immobilization of proteins in their physiological active state via functionalized thiol monolayers on ATR-germanium crystals | Schartner, J., Gavriljuk, K., Nabers, A., Weide, P., Muhler, M., Gerwert, K., Kötting, C. | ChemBioChem | 2014 | 15: 2529-2534 | https://doi.org/10.1002/cbic.201402478 | x | |
164 | Reaction Mechanism of Adenylyltransferase DrrA from Legionella pneumophila Elucidated by Time-Resolved Fourier Transform Infrared Spectroscopy | Gavriljuk, K., Schartner, J., Itzen, A., Goody, R.S., Gerwert, K., Kötting, C. | Journal of the American Chemical Society (JACS) | 2014 | 136: 9338-9345 | https://doi.org/10.1021/ja501496d | ||
163 | A Delocalized Proton-Binding Site within a membrane Protein | Wolf, S., Freier, E., Gerwert, K. | Biophysical Journal | 2014 | 107: 174-184 | https://doi.org/10.1016/j.bpj.2014.05.019 | ||
162 | A modified infrared spectrometer with high time-resolution and its application for investigating fast conformational changes of the GTPase Ras | Lin, J., Gerwert, K., Kötting, C. | Applied Spectroscopy | 2014 | 68: 531-535 | https://doi.org/10.1366/13-07320 | x | |
161 | Automated Identification of Subcellular Organelles by Coherent Anti-Stokes Raman Scattering | El-Mashtoly, S.F., Niedieker, D., Petersen, D., Krauss, S.D., Freier, E., Maghnouj, A., Mosig, A., Hahn, S., Kötting, C., Gerwert, K. | Biophysical Journal | 2014 | 106: 1910-1920 | https://doi.org/10.1016/j.bpj.2014.03.025 | x | |
160 | Label-free imaging of drug distribution and metabolism in colon cancer cells by Raman microscopy. | El-Mashtoly, S.F., Petersen, D., Yosef, H.K., Mosig, A., Reinacher-Schick, A., Kötting, C., Gerwert, K. | Analyst | 2013 | 139: 1155-1161 | https://doi.org/10.1039/c3an01993d | ||
159 | It's in your blood: spectral biomarker candidates for urinary bladder cancer from automated FTIR spectroscopy. | Ollesch, J., Heinze, M., Heise, H.M., Behrens, T., Brüning, T., Gerwert, K. | Journal of Biophotonics | 2013 | 7: 210-221 | https://doi.org/10.1002/jbio.201300163 | ||
158 | The role of protein-bound water molecules in microbial rhodopsins | Gerwert, K., Freier, E., Wolf, S. | BBA Bioenergetics | 2013 | 1837: 606–613 | https://doi.org/10.1016/j.bbabio.2013.09.006 | ||
157 | Vibrational spectroscopy for label-free cancer detection | Gerwert, K., Großerüschkamp, F., Ollesch, J. | Spie | 2013 | 01/07 | https://doi.org/10.1117/2.1201312.005297 | ||
156 | Similarity maps and hierarchical clustering for annotating FT-IR spectral images | Zhong, Q., Yang, C., Großerüschkamp, F., Kallenbach-Thieltges, A., Serocka, P., Gerwert, K., Mosig, A. | BMC Bioinformatics | 2013 | 14: 333 | https://doi.org/10.1186/1471-2105-14-333 | ||
155 | Membrane extraction of Rab proteins by GDP dissociation inhibitor characterized using attenuated total reflection infrared spectroscopy | Gavriljuk, K., Itzen, A., Goody, R.S., Gerwert, K., Kötting, C. | Proceedings of the National Academy of Sciences (PNAS) | 2013 | 110: 13380-13385 | https://doi.org/10.1073/pnas.1307655110 | ||
154 | FTIR spectroscopy of biofluids revisited: an automated approach to spectral biomarker identification | Ollesch, J., Drees, S.L., Heise, H.M., Behrens, T., Brüning, T., Gerwert, K. | Analyst | 2013 | 138: 4092 – 4102 | https://doi.org/10.1039/c3an00337j | ||
153 | The dynamics of the catalytic site in small GTPases, variations on a common motif | Kötting, C., Gerwert, K. | FEBS Letters | 2013 | 587: 2025–2027 | https://doi.org/10.1016/j.febslet.2013.05.021 | ||
152 | Spectral Histopathology of colon cancer tissue sections by Raman imaging with 532 nm excitation provides label free annotation of lymphocytes, erythrocytes and proliferating nuclei of cancer cells | Mavarani, L., Petersen, D., El-Mashtoly, S.F., Mosig, A., Tannapfel, A., Kötting, C., Gerwert, K. | Analyst | 2013 | 138: 4035–4039 | https://doi.org/10.1039/c3an00370a | ||
151 | Monitoring protein-ligand interactions by time-resolved FTIR difference spectroscopy. | Kötting, C., Gerwert K. | Protein-Ligand Interactions; Methods in Molecular Biology | 2013 | 1008: 299-323 | https://doi.org/10.1007/978-1-62703-398-5_11 | x | |
150 | Krebs einfacher diagnostizieren - Welche Rolle spielen Proteine bei der Krebsentstehung? | Gerwert, K. | Rubin | 2013 | ||||
149 | Universal Method for Protein Immobilization on Chemically Functionalized Germanium Investigated by ATR-FTIR Difference Spectroscopy | Schartner, J., Güldenhaupt, J., Mei, B., Rögner, M., Muhler, M., Gerwert, K., Kötting, C. | Journal of the American Chemical Society (JACS) | 2013 | 135: 4079-4087 | https://doi.org/10.1021/ja400253p | ||
148 | Immunohistochemistry, histopathology and infrared spectral histopathology of colon cancer tissue sections | Kallenbach-Thieltges, A., Großerüschkamp, F., Mosig, A., Diem, M., Tannapfel, A., Gerwert, K. | Journal of Biophotonics | 2013 | 6: 88-100 | https://doi.org/10.1002/jbio.201200132 | ||
147 | Catalytic Mechanism of a Mammalian Rab•RabGAP Complex in Atomic Detail | Gavriljuk, K., Gazdag, E. M., Itzen, A., Kötting, C., Goody, R. S., Gerwert, K. | Proceedings of the National Academy of Sciences (PNAS) | 2012 | 109: 21348-21353 | https://doi.org/10.1073/pnas.1214431110 | ||
146 | Time-resolved Fourier Transform Infrared Spectroscopy of the Nucleotide-binding Domain from the ATP-binding Cassette Transporter MsbA | Syberg, F., Suveyzdis, Y., Kötting, C., Gerwert, K., Hofmann, E. | Journal of Biological Chemistry (JBC) | 2012 | 287: 23923-23931 | https://doi.org/10.1074/jbc.M112.359208 | ||
145 | Detailed structure of the H2PO4--GDP intermediate in Ras-GAP decoded from FTIR experiments by biomolecular simulations | Xia, F., Rudack, T., Cui, Q., Kötting, C., Gerwert, K. | Journal of the American Chemical Society (JACS) | 2012 | 134: 20041-20044 | https://doi.org/10.1021/ja310496e | ||
144 | N-Ras forms dimers at POPC membranes | Güldenhaupt, J., Rudack, T., Bachler, P., Mann, D., Triola, G., Waldmann, H.,Kötting, C.,Gerwert, K. | Biophysical Journal | 2012 | 103: 1585-1593 | https://doi.org/10.1016/j.bpj.2012.08.043 | ||
143 | The Role of Magnesium for Geometry and Charge in GTP Hydrolysis, Revealed by Quantum Mechanics/Molecular Mechanics Simulations | Rudack, T., Fei X., Schlitter, J., Kötting, C., Gerwert, K. | Biophysical Journal | 2012 | 103: 293–302 | https://doi.org/10.1016/j.bpj.2012.06.015 | ||
142 | Ras and GTPase-activating protein (GAP) drive GTP into a precatalytic state as revealed by combining FTIR and biomolecular simulations | Rudack, T., Fei X., Schlitter, J., Kötting, C., Gerwert, K. | Proceedings of the National Academy of Sciences (PNAS) | 2012 | 109: 15295-15300 | https://doi.org/10.1073/pnas.1204333109 | ||
141 | Exploring the Multidimensional Free Energy Surface of Phosphoester Hydrolysis with Constrained QM/MM Dynamics | Li, W., Rudack, T., Gerwert, K., Gräter, F., Schlitter, J. | Journal of Chemical Theory and Computation | 2012 | 8: 3596-3604 | https://doi.org/10.1021/ct300022m | ||
140 | Surface attached polyhistidine-tag proteins characterized by FTIR difference spectroscopy | Pinkerneil, P., Güldenhaupt, J., Gerwert, K., Kötting, C. | ChemPhysChem | 2012 | 13: 2649–2653 | https://doi.org/10.1002/cphc.201200358 | ||
139 | Nanoscale distinction of membrane patches – a TERS study of Halobacterium salinarum | Deckert-Gaudig, T., Böhme, R., Freier, E., Sebesta, A., Merkendorf, T., Popp, J., Gerwert, K., Deckert, V. | Journal of BioPhotonics | 2012 | 5: 582–591 | https://doi.org/10.1002/jbio.201100131 | ||
138 | In channelrhodopsin-2 E90 is crucial for ion selectivity and is deprotonated during the photocycle | Eisenhauer, K., Kuhne, J., Ritter, E., Berndt, A., Wolf, S., Freier, E., Bartl, F., Hegemann, P., Gerwert, K. | Journal of Biological Chemistry (JBC) | 2012 | 287: 6904-6911 | https://doi.org/10.1074/jbc.M111.327700 | ||
137b | Prediction of a ligand-binding niche within a human olfactory receptor by combining site-directed mutagenesis with dynamic homology modelling | Gelis, L., Wolf, S., Hatt, H., Neuhaus, E.M., Gerwert, K. | Angewandte Chemie International Edition | 2012 | 51: 1274-1278 | https://doi.org/10.1002/anie.201103980 | ||
137a | Vorhersage der Ligandenerkennung in einem Geruchsrezeptor durch Kombination von ortsgerichteter Mutagenese und dynamischer Homologie-Modellierung | Gelis, L., Wolf, S., Hatt, H., Neuhaus, E.M., Gerwert, K. | Angewandte Chemie | 2012 | 124: 1300-1304 | https://doi.org/10.1002/ange.201103980 | ||
136 | Time-resolved FTIR spectroscopy for monitoring protein dynamics exemplified by functional studies of Ras protein bound to a lipid bilayer | Kötting, C., Güldenhaupt, J., Gerwert, K. | Chemical Physics | 2012 | 396: 72-83 | https://doi.org/10.1016/j.chemphys.2011.08.007 | ||
135 | The Specific vibrational modes of GTP in solution and bound to Ras: a detailed theoretical analysis by QM/MM simulations | Fei, X., Rudack, T., Kötting, C., Schlitter, J., Gerwert, K. | Physical Chemistry Chemical Physics | 2011 | 13: 21451–21460 | https://doi.org/10.1039/c1cp22741f | ||
134 | The structure of active opsin as a basis for identification of GPCR agonists by dynamic homology modelling and virtual screening assays | Schneider, M., Wolf, S., Schlitter, J., Gerwert, K. | FEBS Letters | 2011 | 585: 3587-3592 | https://doi.org/10.1016/j.febslet.2011.10.027 | ||
133 | Structural Basis of Slow Activation Gating in the Cardiac IKs Channel Complex | Strutz-Seebohm, N., Pusch, M., Wolf, S., Stoll, R., Tapken, D., Gerwert, K., Attali, B., Seebohm, G. | Cellular Physiology and Biochemistry | 2011 | 27: 443-452 | https://doi.org/10.1159/000329965 | ||
132 | Proton transfer via a transient linear water-molecule chain in a membrane protein | Freier, E., Wolf, S., Gerwert, K. | Proceedings of the National Academy of Sciences (PNAS) | 2011 | 108: 11435-11439 | https://doi.org/10.1073/pnas.1104735108 | ||
131 | Histidine is involved in coupling proton uptake to electron transfer in photosynthetic proteins | Onidas, D., Stachnik, J. M., Brucker, S., Krätzig, S., Gerwert, K. | European Journal of Cell Biology | 2010 | 89: 983–989 | https://doi.org/10.1016/j.ejcb.2010.08.007 | ||
130 | Label-Free Screening of Drug-protein Interactions by trFTIR Spectroscopic Assays Exemplified by Ras Interactions | Kötting, C., Suveyzdis, Y., Bojja, R., Metzler Nolte, N., Gerwert, K. | Applied Spectroscopy | 2010 | 64: 967-972 | https://doi.org/10.1366/000370210792434341 | x | |
129 | Fourier Transform Infrared (FTIR) Spectroscopy | Gerwert, K., Kötting, C. | Encyclopedia of Life Sciences | 2010 | 1-8 | https://doi.org/10.1002/9780470015902.a0003112.pub2 | x | |
128e | Directional Proton Transfer in Membrane Proteins Achieved through protonated Protein-Bound Water Molecules: A Proton-Diode | Wolf, S., Freier, E., Potschies, M., Hofmann, E., Gerwert, K. | Angewandte Chemie International Edition | 2010 | 49: 6889-6893 | https://doi.org/10.1002/anie.201001243 | ||
128g | Gerichteter Protonentransfer in Membranproteinen mittels protonierter proteingebundener Wassermoleküle: eine Protonendiode | Wolf, S., Freier, E., Potschies, M., Hofmann, E., Gerwert, K. | Angewandte Chemie | 2010 | 122: 7041-7046 | https://doi.org/10.1002/anie.201001243 | ||
127 | Tyr39 of Ran preserves the Ran·GTP gradient by inhibiting GTP hydrolysis | Brucker, S., Gerwert, K., Kötting, C. | Journal of Molecular Biology (JMB) | 2010 | 401: 1–6 | https://doi.org/10.1016/j.jmb.2010.05.068 | ||
126 | Unraveling the mechanism of dual-specificity GAPs | Begoña Sot, B., Kötting, C., Deaconescu, D., Suveyzdis, Y., Gerwert, K., Wittinghofer, A. | The EMBO Journal | 2010 | 29: 1205-1214 | https://doi.org/10.1038/emboj.2010.20 | ||
125 | Spectroscopic investigation of the reaction mechanism of CopB-B, the catalytic fragment from an archaeal thermophilic ATP-driven heavy metal transporter | Völlmecke, C., Kötting, C., Gerwert, K., Lübben, M. | FEBS Journal | 2009 | 276: 6172–6186 | https://doi.org/10.1111/j.1742-4658.2009.07320.x | ||
124 | How does a membrane protein achieve a vectorial proton transfer via water molecules? | Wolf, S., Freier, E., Gerwert, K. | ChemPhysChem | 2008 | 9: 2772-2778 | https://doi.org/10.1002/cphc.200800703 | ||
123 | Dynamik der Proteine | Kötting. C., Gerwert, K. | BIOforum | 2008 | 6/2008, 36-38 | |||
122 | Secondary Structure of Lipidated Ras bound to a Lipid Bilayer | Güldenhaupt, J., Adigüzel, Y., Kuhlmann, J., Waldmann, H., Kötting, K., Gerwert, K. | FEBS Journal | 2008 | 275: 5910-5918 | https://doi.org/10.1111/j.1742-4658.2008.06720.x | ||
121 | Simulations of a G protein-coupled receptor homology model predict dynamic features and a ligand binding site | Wolf, S., Böckmann, S., Höweler, U., Schlitter, J., Gerwert, K. | FEBS Letters | 2008 | 582: 3335-3342 | https://doi.org/10.1016/j.febslet.2008.08.022 | ||
120 | Dynamik der Proteine | Kötting, C., Gerwert, K. | GIT Labor-Fachzeitschrift | 2008 | 9/2008: S. 772–774 | |||
119 | Structural changes of membrane anchored PrPC | Elfrink, K., Ollesch, J., Stöhr, C., Willbold, D., Riesner, D., Gerwert, K. | Proceedings of the National Academy of Sciences (PNAS) | 2008 | 105: 10815-10819 | https://doi.org/10.1073/pnas.0804721105 | ||
118 | Systematic approach to group-specific isotopic labeling of proteins for vibrational spectroscopy | Warscheid, B., Brucker, S., Kallenbach, A., Meyer, H.E., Gerwert, K., Kötting, C. | Vibrational Spectroscopy | 2008 | 48: 28–36 | https://doi.org/10.1016/j.vibspec.2007.11.003 | ||
117 | The GAP arginine finger movement into the catalytic site of Ras increases the activation entropy | Kötting, C., Kallenbach, A., Suveyzdis, Y., Wittinghofer, A., Gerwert, K. | Proceedings of the National Academy of Sciences (PNAS) | 2008 | 105: 6260-6265 | https://doi.org/10.1073/pnas.0712095105 | ||
116 | Secondary structure and distribution of fusogenic LV-peptides in lipid membranes | Ollesch, J., Poschner, B.C., Nikolaus, J., Hofmann, M.W., Herrmann, A., Gerwert, K., Langosch, D. | European Biophysics Journal | 2008 | 37: 435-445 | https://doi.org/10.1007/s00249-007-0233-4 | ||
115 | Role of the arginine finger in Ras?RasGAP revealed by QM/MM calculations | te Heesen, H., Gerwert, K., Schlitter, J. | FEBS Letters | 2007 | 581: 5677-5684 | https://doi.org/10.1016/j.febslet.2007.11.026 | ||
114 | Prion Protein a-to-ß Transition Monitored by Time-Resolved Fourier Transform Infrared Spectroscopy | Ollesch, J., Künnemann, E., Glockshuber, R., Gerwert, K. | Applied Spectroscopy | 2007 | 61: 1025-1031 | https://doi.org/10.1366/000370207782217680 | x | |
113 | Protein Reactions: Resolved with tr-FTIR | Kötting, C., Gerwert, K. | Spectroscopy Europe | 2007 | 19 3: 19-23 | |||
112 | Surface change of Ras enabling effector binding monitored in real time at atomic resolution | Kötting, C., Kallenbach, A., Suveyzdis, Y., Eichholz, C., Gerwert, K. | ChemBioChem | 2007 | 8: 781-787 | https://doi.org/10.1002/cbic.200600552 | ||
111 | Insight into catalysis of a unique GTPase reaction by a combined biochemical and FTIR approach | Chakrabarti, P., Daumke, O., Suveyzdis, Y., Kötting, C., Gerwert, K., Wittinghofer, A. | Journal of Molecular Biology (JMB) | 2007 | 367: 983-995 | https://doi.org/10.1016/j.jmb.2006.11.022 | ||
110 | Proton uptake in the reaction center mutant L210DN from Rhodobacter sphaeroides via protonated water molecules | Hermes, S., Stachnik, J.M., Onidas, D., Remy, A., Hofmann, E., Gerwert, K. | Biochemistry | 2006 | 45: 13741-13748 | https://doi.org/10.1021/bi060742q | ||
109 | Proteinreaktionen: aufgelöst mit trFTIR | Kötting, C., Gerwert, K. | Nachrichten aus der Chemie | 2006 | 54: 959-965 | https://doi.org/10.1002/nadc.20060541006 | x | |
108 | A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein | Kötting, C., Blessenohl, M., Suveyzdis, Y., Goody, R.S., Wittinghofer, A., Gerwert, K. | Proceedings of the National Academy of Sciences (PNAS) | 2006 | 103: 13911-13916 | https://doi.org/10.1073/pnas.0604128103 | ||
107 | Polarised FTIR Spectroscopy in Conjunction with in situ H/D Exchange reveals the Orientation of Protein Internal Carboxylic Acids | Garczarek, F., Gerwert, K. | Journal of the American Chemical Society (JACS) | 2006 | 128: 28-29 | https://doi.org/10.1021/ja056488r | ||
106 | A time-resolved Fe-specific X-ray absorption experiment yields no evidence for a Fe2+->Fe3+ transition during QA --> QB electron transfer in the photosynthetic reaction center | Hermes, S., Bremm, O., Garczarek, F., Derrien, V., Liebisch, P., Loja, P., Sebban, P., Gerwert, K., Haumann, M. | Biochemistry | 2006 | 45: 353-359 | https://doi.org/10.1021/bi0515725 | ||
105 | Functional waters in intraprotein proton transfer monitored by FTIR difference spectroscopy. | Garczarek, F., Gerwert, K. | Nature | 2006 | 439: 109-112 | https://doi.org/10.1038/nature04231 | ||
104 | Monitoring Protein-Protein Interactions by Time-resolved FTIR Difference Spectroscopy | Kötting, C., Gerwert, K. | Protein-Protein Interactions; A molecular cloning Manual, 2nd edition | 2005 | x | |||
103 | Monitoring Protein-Ligand Interactions by Time-resolved FTIR Difference Spectroscopy | Kötting, C., Gerwert, K. | Protein-Ligand Interactions; Methods in Molecular Biology | 2005 | https://doi.org/10.1385/1-59259-912-5:261 | x | ||
102 | Theoretical IR Spectroscopy Based on QM/MM Calculations Provides Changes in Charge Distribution, Bond Length, and Bond Angles of the GTP Ligand Induced by the Ras-Protein | Klähn, M., Schlitter, J., Gerwert, K. | Biophysical Journal | 2005 | 88: 3829-3844 | https://doi.org/10.1529/biophysj.104.058644 | ||
101 | Proteins in Action Monitored by Time-Resolved FTIR Spectroscopy | Kötting, C., Gerwert, K. | ChemPhysChem | 2005 | 6: 881-888 | https://doi.org/10.1002/cphc.200400504 | ||
100 | Light-induced reactions of Escherichia coli DNA photolyase monitored by Fourier transform infrared spectroscopy | Schleicher, E., Heßling, B., Illarinova, V., Bacher, A., Weber, S., Richter, G., Gerwert, K. | FEBS Journal | 2005 | 272: 1-12 | https://doi.org/10.1111/j.1742-4658.2005.04617.x | ||
099 | Proton binding within a membrane protein by a protonated water cluster | Garczarek, F., Brown, L.S., Lanyi, J.K., Gerwert, K. | Proceedings of the National Academy of Sciences (PNAS) | 2005 | 102: 3633-3638 | https://doi.org/10.1073/pnas.0500421102 | ||
098 | Water Dynamics Simulation as a Tool for Probing Proton Transfer Pathways in a Heptahelical Membrane Protein | Kandt, C., Gerwert, K., Schlitter, J. | PROTEINS: Structure, Function, and Bioinformatics | 2005 | 58: 528-537 | https://doi.org/10.1002/prot.20343 | ||
097 | Time-resolved FTIR studies provide activation free energy, activation enthalpy and activation entropy for GTPase reactions | Kötting, C., Gerwert, K. | Chemical Physics | 2004 | 307: 227-232 | https://doi.org/10.1016/j.chemphys.2004.06.051 | ||
096 | Reply to „Complementaries and Convergence of Results in Bacteriorhodopsin Trimer Simulations“ | Kandt, C., Schlitter, J., Gerwert, K. | Biophysical Journal | 2004 | 87: 1396-1396 | https://doi.org/10.1529/biophysj.104.045526 | ||
095 | The Assignment of the Different Infrared Continuum Absorbance Changes Observed in the 3000-1800-cm –1 Region during the Bacteriorhodopsin Photocycle | Garczarek, F., Wang, J., El-Sayed, M. A., Gerwert, K. | Biophysical Journal | 2004 | 87: 2676-2682 | https://doi.org/10.1529/biophysj.104.046433 | ||
094 | IR Spectra of Phosphate Ions in Aqueous Solution : Predictions of a DFT/MM Approach Compared with Observations | Klähn, M., Mathias, G., Kötting, C., Nonella, M., Schlitter, J., Gerwert, K., Tavan, P. | The Journal of Physical Chemistry A | 2004 | 108: 6186-6194 | https://doi.org/10.1021/jp048617g | ||
093 | Fourier Transform Infrared Spectroscopy on the Rap•RapGAP Reaction, GTPase Activation without an Arginine Finger | Chakrabarti, P., Suveyzdis, Y., Wittinghofer, A., Gerwert, K. | Journal of Biological Chemistry (JBC) | 2004 | 279: 46226-46233 | https://doi.org/10.1074/jbc.M405603200 | ||
092 | De Novo design of conformationally flexible transmembrane peptides driving membrane fusion | Hofmann, M. W., Weise, K., Ollesch, J., Agrawal, P., Stalz, H., Stelzer, W., Hulsbergen, F., deGroot, H., Gerwert, K., Reed, J., Langosch, D. | Proceedings of the National Academy of Sciences (PNAS) | 2004 | 101: 14776-14781 | https://doi.org/10.1073/pnas.0405175101 | ||
091 | FTIR spectroscopy shows structural similarities between photosystems II from cyanobacteria and spinach | Remy, A., Niklas, J., Kuhl, H., Kellers, P., Schrott, T., Rögner, M., Gerwert, K. | European Journal of Biochemistry | 2004 | 271: 563-567 | https://doi.org/10.1046/j.1432-1033.2003.03958.x | ||
090 | Dynamics of Water Molecules in the Bacteriorhodopsin Trimer in Explicit Lipid/Water Environment | Kandt, C., Schlitter, J., Gerwert, K. | Biophysical Journal | 2004 | 86: 705-717 | https://doi.org/10.1016/S0006-3495(04)74149-1 | ||
089 | Zeitaufgelöste trFTIR-Studien zeigen Proteine in Aktion | Bourdos, N., Gerwert, K. | Laborwelt | 2003 | 4: No. 6, 31-34 | |||
088 | Coupling of light-induced electron transfer to proton uptake in photosynthesis | Remy, A., Gerwert, K. | Nature Structural & Molecular Biology | 2003 | 10: 637–644 | https://doi.org/10.1038/nsb954 | ||
087 | Does different orientation of the methoxy groups of ubiquinone-10 in the reaction centre of Rhodobacter sphaeroides cause different binding at QA and QB? | Remy, A., Boers, R.B., Egorova-Zachernyuk, T., Gast, P., Lugtenburg, J., Gerwert, K. | European Journal of Biochemistry | 2003 | 270: 3603-3609 | https://doi.org/10.1046/j.1432-1033.2003.03746.x | ||
086 | Proteins at work monitored by time-resolved FTIR-difference spectroscopy | Gerwert, K. | Biophysical Journal | 2002 | 82: 36 | |||
085 | GTPase mechanism of Ras studied by time-resolved FTIR spectroscopy. | Gerwert, K. | Abstracts Of Papers Of The American Chemical Society | 2002 | 223: C25-C25 | |||
084 | Probing protein folding with time-resolved FTIR spectroscopy - Novel techniques for the investigation of changes in protein conformation | Kauffmann, E., Austin, R. H., Gerwert, K. | B.I.F. Futura | 2001 | 16: 152-158 | |||
083 | Molecular Reaction Mechanisms of Proteins Monitored by Time-resolved FTIR Difference Spectroscopy | Gerwert, K. | Handbook of Vibrational Spectroscopy; Volume 5 - Applications of Vibrational Spectroscopy in Life and Natural Sciences | 2001 | x | |||
082 | pKa Calculations Suggest Storage of an Excess Proton in a Hydrogen-Bonded Water Network in Bacteriorhodopsin. | Spassov, V.Z., Luecke, H., Bashford, D., Gerwert, K. | Journal of Molecular Biology (JMB) | 2001 | 312: 203-219 | https://doi.org/10.1006/jmbi.2001.4902 | ||
081 | Monitoring the GAP Catalyzed H-Ras p21 GTPase Reaction at Atomic Resolution in Real Time. | Allin, C., Ahmadian, M.R., Wittinghofer, A., Gerwert, K. | Proceedings of the National Academy of Sciences (PNAS) | 2001 | 98: 7754 – 7759 | https://doi.org/10.1073/pnas.131549798 | ||
080 | Time-Resolved Detection of Transient Movement of Helices F and G in Doubly Spin-Labeled Bacteriorhodopsin. | Radzwill, N., Gerwert, K., Steinhoff, H.-J. | Biophysical Journal | 2001 | 80: 2856 – 2866 | https://doi.org/10.1016/S0006-3495(01)76252-2 | ||
079 | Lifetimes of intermediates in the beta-sheet to alpha-helix transition of beta-lactoglobulin by using a diffusional IR mixer IR mixer. | Kauffmann, E., Darnton, N.C., Austin, R.H., Batt, C., Gerwert, K. | Proceedings of the National Academy of Sciences (PNAS) | 2001 | 98: 6646 - 6649 | "https://doi.org/10.1073/pnas.101122898 | ||
078 | Structure of the I1 early intermediate of photoactive yellow protein by FTIR spectroscopy. | Brudler, R., Rammelsberg, R., Woo, T.T., Getzoff, E.D., Gerwert, K. | Nature Structural Biology | 2001 | 8: 265 – 270 | https://doi.org/10.1038/85021 | ||
077 | Ras Catalyzes GTP Hydrolysis by Shifting Negative chargees from gamma- to beta-Phosphate as revealed by Time-resolved FTIR Difference Spectroscopy | Allin, C., Gerwert, K. | Biochemistry | 2001 | 40: 3037 – 3046 | https://doi.org/10.1021/bi0017024 | ||
076 | Coupling of Hydrogen Bonding to Chromophore Conformation and Function in Photoactive Yellow Protein. | Brudler, R., Meyer, T.E., Genick, U.K.D., Woo, T.T., Millar, D.P., Gerwert, K., Cusanovich, M.A., Tollin, G.,Getzoff, E.D. | Biochemistry | 2000 | 39: 13478-13486 | https://doi.org/10.1021/bi0009946 | ||
075 | Molecular Reaction Mechanisms of Proteins Monitored by Time-Resolved FTIR and FT-Raman Spectroscopy | Gerwert, K. | ACS Symposium Series; Infrared Analysis of Peptides and Proteins | 2000 | 750: 159-166 | https://doi.org/10.1021/bk-2000-0750.ch008 | ||
074 | Time-Resolved FT-IR Difference Spectroscopy: A Tool to Monitor Molecular Reaction of Proteins | Gerwert, K. | Infrared and Raman Spectroscopy of Biological Materials | 2000 | 193-230 | x | ||
073 | Unraveling Photoexcited Conformational Changes of Bacteriorhodopsin by Time Resolved EPR Spectroscopy | Rink, Th., Pfeiffer, M., Oesterhelt, D., Gerwert, K., Steinhoff, H.-J. | Biophysical Journal | 2000 | 78: 1519-1530 | https://doi.org/10.1016/S0006-3495(00)76704-X | ||
072 | Dual Photoactive Species in Glu46Asp and Glu46Ala Mutants of Photoactive Yellow Protein: a pH Driven Color Transition | Devanathan, S., Brudler, R., Heßling, B., Woo, T.T., Gerwert, K., Getzoff, E.D., Cusanovich, M.A., Tollin, G. | Biochemistry | 1999 | 38: 13766-13772 | https://doi.org/10.1021/bi991634p | ||
071 | Efficient Conditions for the Photoaccumulation of HA- in the Photosynthetic Reaction Centres of Rhodobacter sphaeroides R 26 with Uniformly Labelled Bacteriopheophytin Monitored by Fourier Transform Infrared Difference Spectroscopy | Egorova-Zachernyuk, T., Remy, A., Shkuropatov, A., Gast, P., Hoff, A., Gerwert, K., de Groot, H. | Vibrational Spectroscopy | 1999 | 19: 347-352 | https://doi.org/10.1016/S0924-2031(99)00010-7 | ||
070 | Azide Reduces the Hydrophobic Barrier of the Bacterorhodopsin Proton Channel | Steinhoff, H.-J., Pfeiffer, M., Rink, Th., Burlon, O., Kurz, M., Riesle, J., Heuberger, E., Gerwert, K., Oesterhelt, D. | Biophysical Journal | 1999 | 76: 2702-2710 | https://doi.org/10.1016/S0006-3495(99)77422-9 | ||
069 | Time-Resolved Step-Scan FT-IR Spectroscopy of Noncyclic Reactions | Rammelsberg, R., Gerwert, K. | Proceedings of the Twelfth International Conference on Fourier Transform Spectroscopy | 1999 | x | |||
068 | Molecular Reaction Mechanisms of Proteins Monitored by Time-Resolved FTIR-Spectroscopy | Gerwert, K. | Biological Chemistry | 1999 | 380: 931-935 | https://doi.org/10.1515/BC.1999.115 | ||
067 | Strukturbiologie | Gerwert, K. | Biologie 2000 | 1999 | x | |||
066 | Proteine in Aktion | Gerwert, K. | BIORUBIN | 1999 | x | |||
065 | Site-directed Spin-labeling Reveals the Orientation of the Amino Acid Side-chains in the E-F Loop | Pfeiffer, M., Rink, Th., Gerwert, K., Oesterhelt, D., Steinhoff, H.-J. | Journal of Molecular Biology (JMB) | 1999 | 287: 163-171 | https://doi.org/10.1006/jmbi.1998.2593 | ||
064 | Set-up for time-resolved step-scan FTIR spectroscopy of noncyclic reactions | Rammelsberg, R., Boulas, S., Chorongiewski, H., Gerwert, K. | Vibrational Spectroscopy | 1999 | 19: 143-149 | https://doi.org/10.1016/S0924-2031(99)00013-2 | ||
063 | Elektron transfer induces side chain conformational changes of Glu-286 from cytochrome bo3 | Lübben, M., Prutsch, A., Mamat, B., Gerwert, K. | Biochemistry | 1999 | 38: 2048-2056 | https://doi.org/10.1021/bi981859k | ||
062 | Time-resolved FTIR studies of the GTPase reaction of H-ras p21 reveal a keyrole for the beta-phosphate | Cepus, V., Scheidig, A.J., Goody, R.S., Gerwert, K. | Biochemistry | 1998 | 37: 10263-10271 | https://doi.org/10.1021/bi973183j | ||
061 | Bacteriorhodopsin’s Intramolecular Proton-Release Pathway Consists of a Hydrogen-Bonded Network | Rammelsberg, R., Huhn, G., Lübben, M., Gerwert, K. | Biochemistry | 1998 | 37: 5001-5009 | https://doi.org/10.1021/bi971701k | ||
060 | Step-scan FTIR spectroscopy of the QA-QB?QAQB- transition in Rb. sphaeroides R26 reaction centres | Brudler, R., Gerwert, K. | Photosynthesis Research | 1998 | 55: 261-266 | https://doi.org/10.1023/A:1006034322353 | ||
059 | FTIR photolysis studies of caged compounds | Cepus, V., Ulbrich, C., Allin, C., Troullier, A., Gerwert, K. | Methods in Enzymology | 1998 | 291: 223-245 | https://doi.org/10.1016/s0076-6879(98)91015-1 | x | |
058 | Proteins at work: Time-resolved FTIR studies of bacteriorhodopsin and the GTP-binding protein P21. | Gerwert, K. | Interacting Protein Domains, Their Role in Signal and Energy Transduction | 1997 | 63-72 | https://doi.org/10.1007/978-3-642-60848-3_11 | x | |
057 | Zeitaufgelöste FTIR-Spektroskopie zur Bestimmung molekularer Reaktionsmechanismen von Proteinen | Gerwert, K. | Biospektrum | 1997 | 2: 34-39 | |||
056 | Spin labeling studies of the conformational changes in the vicinity of D36,D38,T46 and E161 of bacteriorhodopsin during the photocycle | Rink, Th., Riesle, J., Oesterhelt, D., Gerwert, K., Steinhoff, H.-J. | Biophysical Journal | 1997 | 73: 983-993 | https://doi.org/10.1016/S0006-3495(97)78131-1 | ||
055 | Reconstitution of Bacteriorhodopsin from the Apoprotein and Retinal studied by Fourier-transform Infrared Spectroscopy | Rüdiger, M., Tittor, J., Gerwert, K., Oesterhelt, D. | Biochemistry | 1997 | 36: 4867-4874 | https://doi.org/10.1021/bi962426p | ||
054 | Molecular reaction mechanisms of proteins monitored by nanosecond step-scan FT-IR difference spectroscopy | Rammelsberg, R., Heßling, B., Chorongiewski, H., Gerwert, K. | Applied Spectroscopy | 1997 | 51: 558-562 | https://doi.org/10.1366/0003702971940585 | ||
053 | Fourier Transform Infrared Double-Flash Experiments Resolve Bacteriorhodopsin’s M1 to M2 Transition | Hessling, B., Herbst, J., Rammelsberg, R., Gerwert, K. | Biophysical Journal | 1997 | 73: 2071-2080 | https://doi.org/10.1016/S0006-3495(97)78237-7 | ||
052 | Redox-FTIR difference spectroscopy using caged electrons reveals contribution of carboxyl groups to the catalytic mechanism of haemcopper oxidases | Lübben, M., Gerwert, K. | FEBS Letters | 1996 | 397: 303-307 | https://doi.org/10.1016/S0014-5793(96)01174-X | ||
051 | Kinetic Isotope effects reveal an ice-like and a liquid-phase-type intramolecular proton transfer in Bacteriorhodopsin | le Coutre, J., Gerwert, K. | FEBS Letters | 1996 | 398: 333-336 | https://doi.org/10.1016/S0014-5793(96)01254-9 | ||
050 | A time resolved FTIR difference spectroscopy study of the SR Ca2+-ATPase: kinetics of the high affinity calcium binding at low temperature | Troullier, A., Gerwert, K., Dupont, Y. | Biophysical Journal | 1996 | 71: 2970-2983 | https://doi.org/10.1016/S0006-3495(96)79537-1 | ||
049 | FTIR spectroscopic characterization of the QA and QB binding sites in Rhodobacter sphaeroides R26 reaction centers. | Brudler, R., de Groot, H.J.M., van Liemt, W.B.S., Gast, P., Hoff, A.J., Lugtenburg, J., Gerwert, K. | The Reaction Center of Photosynthetic Bacteria | 1996 | 395-404 | https://doi.org/10.1007/978-3-642-61157-5_31 | x | |
048 | Wie funktionieren Proteine? | Gerwert, K. | RUBIN | 1995 | 2 | |||
047 | FTIR spectroscopy shows weak symmetric hydrogen bonding of the QB carbonyl groups in Rhodobacter sphaeroides R26 reaction centres | Brudler, R., de Groot, H.J.M., van Liemt, W.B.S., Gast, P., Hoff, A.J., Lugtenburg, J., Gerwert, K. | FEBS Letters | 1995 | 370: 88-92 | https://doi.org/10.1016/0014-5793(95)00805-J | ||
046 | Investigation of fast reactions and intermediates | Gerwert, K. | Infrared and Raman Spectroscopy, Methods and Applications | 1995 | 617-637 | x | ||
045 | Computational Studies on Early Intermediates of Bacteriorhodopsin Photocycle | Engels, M., Gerwert, K., Bashford, D. | Biophysical Chemistry | 1995 | 56: 95-104 | https://doi.org/10.1016/0301-4622(95)00020-X | ||
044 | Chemical reconstitution of a chloride pump inactivated by a single point mutation | Rüdiger, M., Haupts, U., Gerwert, K., Oesterhelt, D. | EMBO Journal | 1995 | 14: 1599-1606 | https://doi.org/10.1002/j.1460-2075.1995.tb07148.x | ||
043 | FTIR investigation of the blue to acid -purple transition of Bacteriorhodopsin by use of induced halide binding | le Coutre, J., Rüdiger, M., Oesterhelt, D., Gerwert, K. | Journal of Molecular Structure | 1995 | 349: 165-168 | https://doi.org/10.1016/0022-2860(95)08735-E | ||
042 | Experimental evidence for hydrogen-bonded network proton transfer in bacteriorhodopsin shown by FTIR spectroscopy using azide as catalyst | le Coutre, J., Tittor, J., Oesterhelt, D., Gerwert, K. | Proceedings of the National Academy of Sciences (PNAS) | 1995 | 92: 4962-4966 | https://doi.org/10.1073/pnas.92.11.4962 | ||
041 | Asymmetric binding of the 1- and 4-C=O groups of QA in Rhodobacter sphaeroides R26 reaction centres monitored by Fourier transform infra-red spectroscopy using site-specific isotopically labelled ubiquinone-10 | Brudler, R., de Groot, H.J.M., van Liemt, W.B.S., Steggerda, W.F., Esmeijer, R., Gast, P., Hoff, A.J., Lugtenburg, J., Gerwert, K. | EMBO Journal | 1994 | 13: 5523-5530 | https://doi.org/10.1002/j.1460-2075.1994.tb06889.x | ||
040 | How Catalizes Azide Proton-Pumping in D96N Mutated Bacteriorhodopsin? | le Coutre, J., Gerwert, K. | Time Resolved Vibrational Spectroscopy VI | 1994 | 256-257 | |||
039 | Time-resolved FTIR-Studies of H-Ras P21 GTPase Activity | Gerwert, K., Cepus, V., Scheidig, A., Goody, R.S. | Time Resolved Vibrational Spectroscopy VI | 1994 | 185-187 | x | ||
038 | Molekulare Reaktionsmechanismen photosynthetischer Membranproteine | Gerwert, K. | FUTURA 1 | 1993 | 13-17 | x | ||
037 | Zeitaufgelöste FTIR-Differenzspektroskopie | Gerwert, K., Souvignier, G. | Nachrichten aus der Chemie, Technik und Laboratorium | 1993 | 41: 950-956 | |||
036 | A Model-Independent Approach to Assigning Bacteriorhodopsin's Intramolecular Reactions to Photocycle Intermediates | Heßling, B., Souvignier, G., Gerwert, K. | Biophysical Journal | 1993 | 65: 1929-1941 | https://doi.org/10.1016/S0006-3495(93)81264-5 | ||
035 | Molecular reaction mechanism of proteins as monitored by time-resolved FTIR spectroscopy | Gerwert, K. | Current Opinion Structural Biology | 1993 | 3: 769-773 | https://doi.org/10.1016/0959-440X(93)90062-P | ||
034 | Time-Resolved FTIR Studies on Bacteriorhodopsin | Gerwert,K. | Time Resolved Vibrational Spectroscopy V | 1992 | 61-64 | x | ||
033 | The azide-effect in D96 --> N/G mutated bacteriorhodopsins monitored by timeresolved FTIR-difference-spectroscopy | le Coutre, J., Gerwert, K. | Structures and Functions of Retinal Proteins | 1992 | 127-130 | x | ||
032 | A new approach to analyse kinetic data of bacteriorhodopsin, factor analysis and decomposition | Heßling, B., Souvignier, G., Gerwert, K. | Structures and Functions of Retinal Proteins | 1992 | 155-158 | x | ||
031 | The proton uptake reactions of Bacteriorhodopsin determined by time-resolved stroboscopic-FTIR-spectroscopy | Souvignier, G., Gerwert, K. | Biophysical Journal | 1992 | 63: 1393-1405 | https://doi.org/10.1016/S0006-3495(92)81722-8 | ||
030 | Molecular reaction mechanism of photosynthetic proteins as determined by FTIR-spectroscopy | Gerwert, K. | BBA Bioenergetics | 1992 | 1101: 147-153 | |||
029 | Time-resolved FTIR studies on proteins | Gerwert, K., Souvignier, G. | Proceedings SPIE 1575, 8th International Conference on Fourier Transform Spectroscopy | 1992 | 431-432 | https://doi.org/10.1117/12.56473 | x | |
028 | Electrostatic calculations of the pKa's of ionazable groups in Bacteriorhodopsin | Bashford, D., Gerwert, K. | Journal of Molecular Biology (JMB) | 1992 | 224: 473-486 | https://doi.org/10.1016/0022-2836(92)91009-E | ||
027 | Light-induced charge separation in Rps. viridis reaction centers monitored by FTIR difference spectroscopy: the Quinone vibrations | Buchanan, S., Michel, H., Gerwert, K. | Biochemistry | 1992 | 31: 1314-1322 | https://doi.org/10.1021/bi00120a006 | ||
026 | FT-Raman Light-Induced Intermediate Spectra of Photobiological Systems | Gerwert, K., Hoffmann, A., Schrader, B. | Proceedings of the 13. International Conference on Raman Spectroscopy | 1992 | 490-491 | x | ||
025 | Investigation of quinone reduction in Rps. viridis by FTIR difference spectroscopy and X-ray diffraction analysis | Buchanan, S., Michel, H., Gerwert, K. | Reaction Centers of Photosynthetic Bacteria | 1990 | 75-85 | x | ||
024 | Comparison of FTIR and FT Raman Spectra of Dark-Adapted and Light-Adapted Bacteriorhodopsin | Gerwert, K., Hoffmann, A., Schrader, B. | Proceedings of the 12. International Conference on Raman Spectroscopy | 1990 | 852-853 | x | ||
023 | Time resolved FTIR difference spectroscopy applied to ultra thin layers of membrane proteins. | Gerwert, K., Souvignier, G., Hess, B. | SPIE, Proceedings of the 7. International Conference on FTIR Spectroscopy | 1990 | 1145: 130-131 | https://doi.org/10.1117/12.969390 | x | |
022 | Simultaneous monitoring of light-induced changes in protein side-group protonation, chromophore, isomerization, and backbone motion of bacteriorhodopsin by time-resolved Fourier-transform infrared spectroscopy | Gerwert, K., Souvignier, G., Hess, B. | Proceedings of the National Academy of Sciences (PNAS) | 1990 | 87: 9774-9778 | https://doi.org/10.1073/pnas.87.24.9774 | ||
021 | FTIR studies of light induced intramolecular processes on crystals and reconstituted reaction centers from rhodopseudomonas viridis | Buchanan, S., Michel, H., Gerwert, K. | Current Research in Photosynthesis | 1990 | 69-72 | https://doi.org/10.1007/978-94-009-0511-5_11 | x | |
020 | Proline residues undergo structural changes during proton pumping in bacteriorhodopsin | Gerwert, K., Hess, B., Engelhard, M. | FEBS Letters | 1990 | 261: 449-459 | https://doi.org/10.1016/0014-5793(90)80613-N | ||
019 | Role of aspartate-96 in proton translocation by bacteriorhodopsin | Gerwert, K., Hess, B., Soppa, J., Oesterhelt, D. | Proceedings of the National Academy of Sciences (PNAS) | 1989 | 86: 4943-4947 | https://doi.org/10.1073/pnas.86.13.4943 | ||
018 | Intramolekulare Proteindynamik - Untersuchungen mit Hilfe zeitaufgelöster Fourier-Transform-Infrarot-Spektroskopie | Gerwert, K. | FUTURA | 1988 | 1/88, 31-36 | x | ||
017 | Light induced intramolecular processes of bacteriorhodopsin monitored by time resolved FTIR (Fourier transform infrared) spectroscopy | Gerwert, K., Hess, B. | The Ion Pumps: Structure, Function, and Regulation | 1988 | 321-326 | x | ||
016 | Initiation of light-induced proton transfers in bacteriorhodopsin monitored by FTIR difference spectroscopy | Gerwert, K., Hess, B. | Biophysical Studies of Retinal Proteins. Proceedings of a Conference in Memory of Laura Eisenstein | 1988 | 144-148 | x | ||
015 | FTIR studies on crystals of photosynthetic reaction centers | Gerwert, K., Hess, B., Michel, H., Buchanan, S. | FEBS Letters | 1988 | 232: 303-307 | https://doi.org/10.1016/0014-5793(88)80758-0 | ||
014 | Investigation of Intramolecular Processes in Proteins by Time Resolved FTIR-Difference Spectroscopy | Gerwert, K., Hess, B. | Mikrochimica Acta | 1988 | 255-258 | https://doi.org/10.1007/BF00476634 | ||
013 | Intramolekulare Proteindynamik untersucht mit zeitaufgelöster Fourier Transform Infrarot-Differenzspektroskopie | Gerwert, K. | Berichte der Bunsengesellschaft für Physikalische Chemie | 1988 | 92: 978-982 | https://doi.org/10.1002/bbpc.198800244 | x | |
012 | Only water-exposed carboxyl groups are protonated during the transition to the cation-free blue bacteriorhodopsin | Gerwert, K., Ganter, U.M., Siebert, F., Hess, B. | FEBS Letters | 1987 | 213: 39-44 | https://doi.org/10.1016/0014-5793(87)81461-8 | ||
011 | Intramolecular protontransfers in bacteriorhodopsin monitored by Fourier transform infrared difference spectroscopy | Gerwert, K., Hess, B. | Interactions of Water in Ionic and Nonionic Hydrates | 1987 | 183-186 | x | ||
010 | Investigation of the M to BR backreaction in bacteriorhodopsin by time resolved FTIR difference spectroscopy | Gerwert, K., Hess, B. | Spectroscopy of Biological Molecules - New Advances | 1987 | 261-263 | |||
009 | FTIR spectroscopy on crystals of the photosynthetic reaction centers from Rhodopseudomonas viridis using an IR microscope. | Gerwert, K., Buchanan, S., Hess, B., Michel, H. | Spectroscopy of Biological Molecules - New Advances | 1987 | 301-303 | x | ||
008 | Evidence for light-induced 13-cis, 14-s-cis, isomerization in bacteriorhodopsin obtained by FTIR difference spectroscopy using isotopically labelled retinals | Gerwert, K., Siebert, F. | EMBO Journal | 1986 | 5: 805-811 | https://doi.org/10.1002/j.1460-2075.1986.tb04285.x | ||
007 | Vibrational analysis of chromophore-configurations in bacteriorhodopsin during the photocycle using FTIR difference spectroscopy | Gerwert, K., Siebert, F., Pardoen, J.A., Winkel, C., Lugtenburg, J. | Spectroscopy of Biological Molecules | 1985 | 373-375 | x | ||
006 | Evidence from FTIR-measurements for a separation of the protonated Schiff base from the counterion into a less polar environment. | Gerwert, K., Siebert, F., Pardoen, J.A., Winkel, C., Lugtenburg, J. | Time-Resolved Vibrational Spectroscopy | 1985 | 259-262 | x | ||
005 | Time-resolved infrared spectroscopy applied to photobiological systems. | Gerwert, K., Rodriguez-Gonzales, R., Siebert, F. | Time-Resolved Vibrational Spectroscopy | 1985 | 259-262 | x | ||
004 | Light-driven protonation changes of internal aspartic acids of bacteriorhodopsin: An investigation by static and time-resolved infrared difference spectroscopy using aspartic acid labeled purple membrane | Engelhard, M., Gerwert, K., Hess, B., Kreutz, W., Siebert. F. | Biochemistry | 1985 | 24: 400-407 | https://doi.org/10.1021/bi00323a024 | ||
003 | The role of carboxylic acid residues in the proton pump mechanism of bacteriorhodopsin (bR): Investigation by time resolved and static IR difference spectroscopy with [4-13C] labelled aspartic acid. | Gerwert, K., Kreutz, W., Mäntele, W., Siebert, F., Engelhard, M., Hess, B. | Photochemistry and Photobiology | 1984 | 39 | x | ||
002 | Fourier-transform infrared spectroscopy applied to rhodopsin. The problem of the protonation state of the retinylidene Schiff base reinvestigated | Siebert, F., Mäntele, W., Gerwert, K. | European Journal of Biochemistry | 1983 | 136: 119-127 | https://doi.org/10.1111/j.1432-1033.1983.tb07714.x | ||
001 | Measurement of photoionisation cross sections for the and excited states of caesium | Gerwert, K., Kollath, K.J. | Journal of Physics B: Atomic and Molecular Physics | 1983 | 16: L217-L221 | https://doi.org/10.1088/0022-3700/16/8/002 |